Cooperation Between of Lipid Peroxidation and
Oxidative Phosphorylation
in the Brain Mitokhordial Fraction under the
Conditions of Hypoxia
It was shown that processes of oxidative
phosphorylation and peroxidation of lipids as well as the quantitative changes
of cytochrom contents under the conditions of experimental hypoxia are
accompanied by the significant abnormalities. The data obtained have
demonstrated that abnormalities mentioned are charactezed by activation of free
radical peroxidation reactions, by the lowering of the cytochromes quality and
by the depression of the intensity of phosphorilation
reactions.
These results spray the light on
the modern understandings of pathogenetical mechanisms, which are under lying in
the base of hypoxia.